Investigation of some acute phase proteins, cytokines and hepcidin values in feline enteric corona virus antibodies and feline infectious peritonitis antigen positive cats

Feline Infectious Peritonitis (FIP) is a fatal disease caused by feline coronaviruses. The causative agent Virus, mutation of Enteric Coronavirus. Corona Virus very common in the cat population. In infected cats, development FIP depends on cat's immune response. more young and old cats because animals have weaker system. acute phase response complex systemic reaction that occurs as to or chronic inflammatory processes such infection, neoplasia immunological disorders, tissue damage, trauma surgery. study material included 15 with presumptive (study group) 10 healthy (control group). Of 9 (60%) showed dry 6 (40%) effusive form. Serum amyloid A (SAA), haptoglobin (Hp), α1-acid glycoprotein (AGP), albumin, interleukin-6 (IL-6), hepcidin, alanine-amino transferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), blood urea nitrogen(BUN), creatinine levels were measured serum collected from both groups. There no difference between wet albumin values; haptoglobin, glycoprotein, SAA hepcidin values significantly different two IL-6, significant It was also concluded may be used biomarker like other proteins.